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Kudsk Dyer posted an update 4 days, 17 hours ago
Nearly half of all marijuana users reported driving after use during the past 30 days, and did not differ between males and females. Prevalence of driving after using marijuana was significantly higher among heavy users (PR = 2.8; 95% CI 2.1-3.6). A higher prevalence of driving after drinking alcohol (PR = 1.7; 95% CI 1.5-1.9) was also found among those who had driven after using marijuana.
Among adolescent marijuana users, the prevalence of driving after using marijuana was high. Enhanced surveillance, prevention, and control measures are necessary to mitigate the negative impacts of marijuana consumption and related behaviors.
Among adolescent marijuana users, the prevalence of driving after using marijuana was high. Enhanced surveillance, prevention, and control measures are necessary to mitigate the negative impacts of marijuana consumption and related behaviors.
Surgical options for breast cancer are numerous and span multiple surgical disciplines. Decision analyses aid surgeons in making the most cost-effective choice, thus reducing health care expenditure while maximizing patient outcome. In this study, we aimed to evaluate existing breast surgery cost-effectiveness literature against the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) validated scoring system.
A PRISMA search was performed for cost-effectiveness within breast surgery. Articles were scored with CHEERS criteria on a 0-24 scale and qualitative data were collected. Subgroup analysis was performed comparing pre-CHEERS (published in 2013 or earlier) and post-CHEERS (published in 2014 or later) cohorts. Chi-squared analysis was performed to compare where studies lost points between cohorts.
Of 2279 articles screened, 46 articles were included. The average CHEERS score was 18.18. Points were most often lost for characterizing heterogeneity, followed by discount rate, incremental costs and outcomes, and abstract. Quality-adjusted life year was the most commonly used health outcome, with visual model or analog scales as the most commonly used measure of effectiveness obtained primarily from surgeons or physicians. Most articles characterized uncertainty by deterministic sensitivity analysis, followed by both deterministic and probabilistic, then probabilistic. Average CHEERS scores were similar between pre- and post-CHEERS cohorts (17.67 vs. 18.40,
> .05) There were several significant differences in where articles lost points between pre- and post-CHEERS cohorts.
In order to standardize the reporting of results, cost-effectiveness studies in breast surgery should adhere to the current CHEERS criteria and aim to better characterize heterogeneity in their analyses.
In order to standardize the reporting of results, cost-effectiveness studies in breast surgery should adhere to the current CHEERS criteria and aim to better characterize heterogeneity in their analyses.A common technique for eliciting subjective probabilities is to provide a set of exclusive and exhaustive events and ask the assessor to estimate the probabilities of such events. However, such subjective probabilities estimations are usually subjected to a bias known as the partition dependence bias. AMI-1 solubility dmso This study aims to investigate the effect of state space partitioning and the level of knowledge on subjective probability estimations. The state space is partitioned into full, collapsed, and pruned trees, while the knowledge is manipulated into low and high levels. A scenario called “Best Bank Award” was developed and a 2 × 3 experimental design was employed to explore the effect of the level of knowledge and the partitioning of the state space on the subjective probability. A total of 627 professionals participated in the study and 543 valid responses were used for analysis. The results of two-way ANOVA with the Tukey HSD test for post hoc analysis indicate a mean probability of 24.2% for the full tree, which is significantly lower than those of the collapsed (35.7%) as well as pruned (36.3%) trees. Moreover, there is significant difference in the mean probabilities between the low (38.1%) and high (24.9%) knowledge levels. The results support the hypotheses that the partitioning of the state space as well as the level of knowledge affects subjective probability estimation. The study demonstrates that regardless of the level of knowledge, the partition dependence bias is robust. However, the subjective probability accuracy improves with more knowledge.
Geriatric burn trauma patients (age ≥65years) have a 5-fold higher mortality rate than younger adults. With the population of the US aging, the number of elderly burn and trauma patients is expected to increase. A past study using the National Burn Repository revealed a linear increase in mortality for those >65years old. We hypothesized that octogenarians with burn and trauma injuries would have a higher rate of in-hospital complications and mortality, than patients aged 65-79years old.
The Trauma Quality Improvement Program (2010-2016) was queried for burn trauma patients. To detect mortality risk a multivariable logistic regression model was used.
From 282 patients, there were 73 (25.9%) octogenarians and 209 (74.1%) aged 65-79years old. The two cohorts had similar median injury severity scores (16 vs. 15 in octogenarians,
= .81), total body surface area burned (
= .30), and comorbidities apart from an increased smoking (12.9% vs. 4.1%,
= .04) and decreased hypertension (52.2% vs. 65.8%,
= .04) in the younger cohort. Octogenarians had similar complications, including acute respiratory distress syndrome, pulmonary embolism, deep vein thrombosis (
> .05), and mortality (15.1% vs. 10.5%,
= .30), compared to the younger cohort. Octogenarians were not associated with an increased mortality risk (odds ratio 1.51, confidence interval 0.24-9.56,
= .67).
Among burn trauma patients ≥65years, age should not be a sole predictor for mortality risk. Continued research is necessary in order to determine more accurate approaches to prognosticate mortality in geriatric burn trauma patients, such as the validation and refinement of a burn-trauma-related frailty index.
Among burn trauma patients ≥65 years, age should not be a sole predictor for mortality risk. Continued research is necessary in order to determine more accurate approaches to prognosticate mortality in geriatric burn trauma patients, such as the validation and refinement of a burn-trauma-related frailty index.