• Huber Hardy posted an update 1 day, 19 hours ago

    A 52-year-old woman with a strong family history of breast cancer was diagnosed as having triple-negative breast cancer (TNBC) in her right breast. Neoadjuvant chemotherapy (NAC; four cycles of epirubicin/cyclophosphamide/5-fluorouracil) was performed, followed by breast-conserving surgery and axillary lymph node dissection. Histopathological analysis of the surgical specimens demonstrated a few focal tumor cells remaining in the stroma, but not a pathological complete response (pCR). Weekly paclitaxel was subsequently added to the treatment regimen. A total of 17 months after the adjuvant treatments, TNBC recurred in her left breast with massive lymph node metastasis. Because of the early recurrence after standard treatment, NAC was administered together with carboplatin and paclitaxel. Histopathological analysis of the partially resected breast and axillary lymph nodes demonstrated a pCR. No recurrent disease was found 2 years after the second TNBC treatment. This case underlines the importance of platinum-based chemotherapy and prophylactic mastectomy for patients with BRCA dysfunction.A 49-year-old woman presented with cough, and chest X-rays showed an abnormal shadow. Chest computed tomography showed an anterior mediastinal 40-mm mass with massive calcification. The patient underwent mediastinal tumor excision performed using video-assisted thoracoscopic surgery. Pathological findings revealed the tumor to be a type B3 thymoma, with massive calcification occupying almost all of the thymoma. Due to high risk of recurrence, we performed completion thymectomy. Pathological findings revealed no remaining thymoma tissue in the residual thymus. Mediastinal tumor with entire calcification could be a candidate for surgical excision.Resection and anastomosis of small intestine during colic can lead to adhesions and recurrent colic. Ipatasertib Several methods are available to reduce the rate of adhesions in the postoperative period, such as the use of serosal barriers. Surgical glues form a smooth surface, are fast to apply, and could reduce surgery time when performing anastomosis. A recently developed UV-polymerizable methacrylate adhesive (UV-PMA) is designed to anchor into the biological tissues’ top surface offering sealant and a smooth cover over the anastomosis site. This adhesive was used ex vivo on fifteen samples of equine jejunum as the second layer of a two-layer anastomosis (1L-UV-PMA group) and compared to a two-layer anastomosis (simple continuous pattern covered with a Cushing pattern; 2L-CT group), in terms of feasibility, bursting strength pressure (BSP), luminal diameter reduction (LDR), and time of construction. Data were analysed using a paired t-test or a chi2-test (P less then 0.05). The results showed no statistical difference in BSP, LDR, or any mode of failure between the two anastomosis types. However, the glue anastomosis formed a tunnel-like anastomosis and shredded under pressure, before apparition of leakage, preventing its usage in clinical cases with this methodology. It was concluded that modification of the technique is warranted before testing in clinical cases. A preprint of a former version of the manuscript is available on researchsquare.com, which was not conducted to print and publication after peer reviewing. Since then, the manuscript has been modified to this current version.With the development of science and technology, more and more operations are performed in the cardiac catheterization laboratory. During such operations, a lot of relevant imaging data need to be retained. These imaging data can be used for clinical and scientific research and teaching applications, but imaging data security has also become an increasingly important issue. This article is based on the Internet of Things cardiac catheterization laboratory information management system image data security mechanism system research. First of all, this article adopts the literature method to study the application research of the Internet of Things technology in the medical field, as well as the relevant medical imaging data security technology methods. Then, the medical image data security mechanism was designed, and the image data security model of the cardiac catheterization laboratory information management system based on the Internet of Things was established. Finally, the application of decentralized management of the Internet of Things RFID technology on medical equipment and the security of the application of this technology on medical imaging data are analyzed, and finally a conclusion is drawn. The image data security mechanism established in this article is based on the Internet of Things technology. The security rate of image information data reaches more than 95%, the information data security level reaches level 1, and the average data missing rate is only 4.7%. It is a brand-new breakthrough, hoping to further improve the efficiency of hospital information management and protect the safety of medical information.In martial arts, data mining technologies are used to describe and analyze the moves of athletes and changes in the process and sequences. Martial arts is a process in which athletes use all kinds of strengths and actions to make offensive and defensive changes according to the tactics of opponents. One such martial arts is Wushu arts as it has a long history in reference to Chinese martial arts. During the Wushu competition, Wushu athletes show their adaptability and technical level in complex, random, and nonlinear competitive abilities, organized and systematic skills, tactics, and position movement. Using data mining techniques, in-depth mining a particular type of martial arts competition technology and tactics behind statistical data, and using the data to find the law of change to solve some problems, for martial arts athletes in daily training to develop technology and tactics and improve competition results, is the practical significance of data mining in martial arts athletes competition. This research explored the relationship between goal-oriented and mental intensity and their effect on competitive success outcomes.